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*Contents are tentative and subject to change prior to publication. List denotes lead author only.
Prologue
Joseph Pancrazio
SECTION I: INTRODUCTION
Introduction
Elliot S. Krames
Chapter 1: What Is Neuromodulation?
Elliot S. Krames, Ali R. Rezai, P. Hunter Peckham, and Farag Aboelsaad
Chapter 2: Neuromodulation: A Historical Perspective
Philip L. Gildenberg
Chapter 3: Neuromodulation Technologies: Whom Do We Serve?
Allen R. Dyer and Mary Pat Aardrup
Chapter 4: Challenges in Moving Toward Product Development
Paul Meadows
Chapter 5: The Birth of an Industry
James Cavuoto
Chapter 6: Beginnings of the Societies
Ross Davis, Philip L. Gildenberg, Giancarlo Barolat, Elliot S. Krames, Dejan Popovic, and Paul Meadows
Chapter 7: Clinical Study Design
Daniel B. Carr and Anthony Eidelman
Chapter 8: Psychological Issues and Evaluation for Patients Undergoing Implantable Technology
Daniel M. Doleys
Chapter 9: Deep Brain Stimulation: Ethical Issues in Clinical Practice and Neurosurgical Research
Joseph J. Fins
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SECTION II: FUNDAMENTALS OF NEUROMODULATION
Introduction
Narendra Bhadra, J. Thomas Mortimer, and P. Hunter Peckham
Chapter 10: Anatomy of the Nervous System
Joshua M. Rosenow
Chapter 11: Fundamentals of Electrical Stimulation
J. Thomas Mortimer and Narendra Bhadra
Chapter 12: Neuromodulation and Neuronal Plasticity
Alon Y. Mogilner
Chapter 13: Gene-Based Neuromodulation
Thais Federici, Jonathan Riley, and Nicholas Boulis
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SECTION II A: Mechanisms
Introduction
Chapter 14: Principles of Electric Field Generation for Stimulation of the Central Nervous System
Warren M. Grill
Chapter 15: Mechanisms of Action of Deep Brain Stimulation: A Review
Kendall Lee, Charles Blaha, and Jonathan M. Bledsoe
Chapter 16: Computational Modeling of Deep Brain Stimulation
Cameron C. McIntyre
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SECTION III: BIOMEDICAL ENGINEERING CONSIDERATIONS
Introduction
Joseph Pancrazio and P. Hunter Peckham
Chapter 17: Electrodes for the Neural Interface
Dustin J. Tyler and Katharine H. Polasek
Chapter 18: Implantable Neural Stimulators
P. Hunter Peckham and D. Michael Ackermann, Jr.
Chapter 19: Designing a Neural Interface System to Restore Mobility
John P. Donoghue and Leigh Hochberg
Chapter 20: MRI Safety and Neuromodulation Systems
Frank G. Shellock
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SECTION IV: NEUROMODULATION FOR CHRONIC PAIN
Introduction
Elliot S. Krames and Andre Machado
Chapter 21: Physiology and Pathophysiology of Chronic Pain
Joshua M. Rosenow
Chapter 22: The Endogenous Neuromodulation System
Allan I. Basbaum, Joao Braz, Michael H. Ossipov, and Frank Porreca
Chapter 23: Management Strategies for Chronic Pain
Rollin M. Gallagher
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SECTION IV A: Periphery and Spinal Cord Electrical Stimulation for Non-Visceral Pain
Introduction
Chapter 24: Transcutaneous Electrical Nerve Stimulation (TENS): A Review
Kathleen Sluka, Howard S. Smith, and Deirdre M. Walsh
Chapter 25: Mechanisms of Spinal Cord Stimulation in Neuropathic and Ischemic Pain Syndromes
Bengt Linderoth, Robert D. Foreman, and Björn A. Meyerson
Chapter 26: The Cost-Effectiveness of Spinal Cord Stimulation
Richard B. North, Jane Shipley, and Rod S. Taylor
Chapter 27: SCS for Painful Neuropathies
Giancarlo Barolat
Chapter 28: Neurostimulation in the Treatment of Complex Regional Pain Syndrome
Joshua P. Prager
Chapter 29: Peripheral Nerve Stimulation (PNS) for Pain Peripheral Neuralgia and CRPS
Michael Stanton-Hicks
Chapter 30: Occipital Neurostimulation (ONS) for Treatment of Intractable Headache Syndromes
Richard L. Weiner and Kenneth M. Alo`
Chapter 31: Subcutaneous Targeted Stimulation
Teodor Goroszeniuk and Sandesha Kothari
SECTION IV B: Infusional Therapies for Pain
Introduction
Chapter 32: Relevant Anatomy for Spinal Delivery
Timothy R. Deer, Matthew Ranson, and Douglas Stewart
Chapter 33: The Rational Use of Intrathecal Opioid Analgesics
Elliot S. Krames and Mouchir Harb
Chapter 34: Intrathecal Analgesics, Choice of System
Marshall D. Bedder
Chapter 35: Intrathecal Non-Opioid Analgesics for the Control of Pain
Enrique Reig, David Abejón, and Elliot S. Krames
Chapter 36: Compounding Intrathecal Drugs
Richard L. Rauck
Chapter 37: Intracerebroventricular Opioid Administration for Chronic Pain
Katherine E. Groothuis and Robert M. Levy
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SECTION IV C: Brain Stimulation for Pain
Introduction
Chapter 38: Deep Brain Stimulation for Pain
Erlick A. C. Pereira, Sarah L. F. Owen, Alexander L. Green, and Tipu Z. Aziz
Chapter 39: Deep-Brain Stimulation of the Posterior Hypothalamus in Chronic Cluster Headache
A. Franzini, G. Messina, M. Leone, G. Bussone, C. Marras, G. Tringali, and G. Broggi
Chapter 40: Motor Cortex Stimulation for the Treatment of Neuropathic Pain
Jean Paul Nguyen, Jean Pascal Lefaucheur, Sylvie Raoul, Vincent Roualdes, Yann Pereon, and Yves Keravel
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SECTION V: NEUROMODULATION FOR MOVEMENT DISORDERS
Introduction
Donald Weisz and Ron L. Alterman
Chapter 41: Movement Disorders: Anatomy and Physiology Relevant to Deep Brain Stimulation
Brian Harris Kopell, Gregory F. Molnar, and Bradley Hiner
Chapter 42: Deep Brain Stimulation in Parkinson's Disease
Karl Sillay and Philip Starr
Chapter 43: Deep Brain Stimulation for Tremor
Adam P. Burdick, Michael S. Okun, and Kelly D. Foote
Chapter 44: Infusion Therapy for Movement Disorders
Joseph C. Hsieh and Richard D. Penn
Chapter 45: Deep Brain Stimulation for Torsion Dystonia
Ron L. Alterman and Michele Tagliati
Chapter 46: Deep Brain Stimulation in Tourette Syndrome
Veerle Visser-Vandewalle, Yasin Temel, and Linda Ackermans
Chapter 47: Surgical Management of Hemifacial Spasm and Meige Syndrome
Hyun Ho Jung and Jin Woo Chang
Chapter 48: Deep Brain Stimulation (DBS) of the Medial Thalamus for Movement Disorders: The Role of the Centromedianum-Parafascicular Complex
Paolo Mazzone, Alessandro Stefani, and G. Della Marca
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SECTION VI: NEUROSTIMULATION FOR EPILEPSY
Introduction
Ash Sharan and Ali R. Rezai
Chapter 49: Epilepsy: Anatomy, Physiology, Pathophysiology, and Disorders
David King-Stephens
Chapter 50: Vagus Nerve Stimulation for Epilepsy
Arun Paul Amar, Michael L. Levy, Charles Y. Liu, and Michael L. J. Apuzzo
Chapter 51: Deep Brain Stimulation for Epilepsy
Casey H. Halpern, Uzma Samadani, Brian Litt, Jurg L. Jaggi, and Gordon H. Baltuch
Chapter 52: Cerebellar Stimulation for Epilepsy
Steven Falowksi, Ashwini D. Sharan, Amanda Celii, and
Ross Davis
Chapter 53: Closed Loop Stimulation in the Control of Focal Epilepsy
J. Smith, K. Fountas, M. Murro, Y. Park, P. Jenkins, D. Greene, and R. Esteller
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SECTION VII: NEUROMODULATION FOR PSYCHIATRIC DISORDERS
Introduction
Benjamin D. Greenberg
Chapter 54: Electroconvulsive Therapy, Transcranial Magnetic Stimulation, and Vagus Nerve Stimulation for Depression
Linda L. Carpenter, Margaret C. Wyche, Gerhard M. Friehs, and John O'Reardon
Chapter 55: Electrical Brain Stimulation in Treatment-Resistant Obsessive-Compulsive Disorder: Parcellation, and Cyto- and Chemoarchitecture of the Bed Nucleus
of the Stria Terminalis, A Review
Kris van Kuyck, Loes Gabriëls, and Bart Nuttin
Chapter 56: Deep Brain Stimulation for Highly Refractory Depression
Benjamin D. Greenberg
Chapter 57: Surgical Treatment for Refractory Drug Addictions
Bomin Sun, Shikun Zhan, Dianyou Li, and Hemmings Wu
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SECTION VIII: NEUROMODULATION FOR FUNCTIONAL RESTORATION
Introduction
P. Hunter Peckham
Chapter 58: Stimulation for the Return of Hearing
Blake S. Wilson and Michael F. Dorma
Chapter 59: The Development of Visual Prosthetic Devices to Restore Vision to the Blind
Muhammad Memon and Joseph F. Rizzo III
Chapter 60: Stimulation for Return of Function after Stroke
John Chae, Jayme Knutson, and Lynne Sheffler
Chapter 61: Cortical Stimulation for the Treatment of Motor Deficits following Ischemic Stroke
Janna Silverstein and Robert M. Levy
Chapter 62: Stimulation for Return of Upper and Lower Extremity Function
Kevin L. Kilgore, Michael W. Keith, and P. Hunter Peckham
Chapter 63: A Neural Prosthesis for Obstructive Sleep Apnea
Dominique M. Durand
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SECTION IX: NEUROMODULATION OF BODY ORGANS
Introduction
Elliot S. Krames
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SECTION IX A: Cardiovascular
Chapter 64: Neuronal Control of the Heart: Neuromodulation
Jeffrey L. Ardell and Robert D. Foreman
Chapter 65: Disorders of Pacing
Thomas Dresing
Chapter 66: Cardiac Pacemakers—Past, Present, and Future
Guy Amit and Kara J. Quan
Chapter 67: Cardiac Defibrillators
Thomas Dresing
Chapter 68: Spinal Cord Stimulation for Peripheral Vascular Disorders
Svante Horsch and Stefan Schulte
Chapter 69: Spinal Cord Stimulation for Refractory Angina
Mike J. L. DeJongste and Robert D. Foreman
Chapter 70: Neuromodulation and Hypertension
Tara M. Mastracci and Roy K. Greenberg
Chapter 71: Neuromodulation of Cardiac Dysfunction
Sandra Machado, Kwangdeok Lee, and Marc S. Penn
SECTION IX B: Gastrointestinal
Chapter 72: Neural Control of the Colon
Beverley Greenwood-Van Meerveld and Robert D. Foreman
Chapter 73: Spinal Cord Stimulation for Gastrointestinal Painful Disorders
Leonardo Kapural
Chapter 74: Gastric Stimulation for Dysmotility Disorders and Obesity
Cristian Sevcencu
Chapter 75: Intestinal Electrical Stimulation: Methodologies, Effects, Mechanisms, and Applications
Jieyun Yin and Jiande D. Z. Chen
SECTION IX C: Genitourinary
Chapter 76: Neurophysiology of the Genitourinary Organs
William C. de Groat and Firouz Daneshgari
Chapter 77: Sacral Nerve Root Stimulation for Painful Bladder Syndrome/Interstitial Cystitis
Adnan A. Al-Kaisy and K. Riaz Khan
Chapter 78: Neuromodulation for Voiding Dysfunction
Sarah McAchran, Raymond Rackley, and Sandip Vasavada
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SECTION X: EMERGING APPLICATIONS OF NEUROMODULATION
Introduction
Elliot S. Krames and Ali R. Rezai
Chapter 79: Deep Brain Stimulation for Obesity
Michael Y. Oh, David B. Cohen, and Donald M. Whiting
Chapter 80: Deep Brain Stimulation for Blood Pressure Control
Erlick A. C. Pereira, Alexander L. Green, and Tipu Z. Aziz
Chapter 81: Tinnitus
Brian Harris Kopell and David Friedland
Chapter 82: Brain and Cerebrospinal Fluid Infusion Therapies for the Treatment of CNS Disease
Daniel J. Abrams
Chapter 83: Deep Brain Stimulation for Cognitive Neuromodulation
Nicholas D. Schiff
Chapter 84: Novel Neuromodulation Approaches for Alzheimer's Disease and Other Neurodegenerative Conditions
Julie G. Pilitsis and Roy A. E. Bakay
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SECTION XI: NEUROMODULATION DEVICE IMPLANT TECHNIQUES
Introduction
Elliot S. Krames
Chapter 85: Deep Brain Stimulation: Surgical Technique
Andre G. Machado, Alon Y. Mogilner, and Ali R. Rezai
Chapter 86: Spinal Cord Stimulation: Placement of Surgical Leads via Laminotomy—Techniques and Benefits
Krishna Kumar, Goran Lind, Jaleh Winter, Shivani Gupta, Sharon Bishop, and Bengt Linderoth
Chapter 87: Peripheral Nerve Stimulation
Michael Stanton-Hicks
Chapter 88: Subcutaneous Peripheral Nerve Field Stimulation for Intractable Pain
Giancarlo Barolat
Chapter 89: Surgical Placement of Occipital Leads
Richard L. Weiner
Chapter 90: Surgical Technique: Intrathecal Medication Delivery System Implantation
Joshua M. Rosenow
Chapter 91: The Surgical Technique of Vagus Nerve Stimulator Implantation
Jeffrey W. Cozzens
Appendices
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